A Market That Rewarded Execution

In 2025, enterprise AI stopped being about potential and started being about proof. The question shifted from “Can this work?” to “Can this be deployed, governed, and trusted at scale?” As organizations moved past experimentation, expectations sharpened —  and execution became the differentiator.

Three dynamics were unmistakable:

• The Commoditization of Models: As large language models continue to commoditize, enterprise value is shifting toward orchestration, routing, governance, and integration. Performance increasingly depends on how models are deployed within complex systems, not which model is selected.

• Enterprise Readiness as the Bottleneck: Enterprises are now racing to prepare their data, systems, and workflows for AI at scale. Adoption is less about experimentation and more about infrastructure, security, and long-term reliability.

• Bottom-Up Adoption Across Daily Workflows: AI adoption wasn’t driven only from the top down. As enterprises focused on enabling employees to use these tools in their day-to-day work, adoption increasingly spread across tasks, teams, and workflows.

As these shifts take hold across industries, Myriad Venture Partners showed that a model built at the intersection of venture capital and enterprise adoption doesn’t just work — it works repeatedly, at scale. With enterprise AI entering its execution phase, success increasingly depends on trusted partners who can bridge early insight with real-world deployment.

2025: The First Full Year of the Myriad Model

At its core, the Myriad Model pairs venture capital and venture-backed startups with deep enterprise and operator engagement, helping founders scale faster while giving enterprises confidence to adopt emerging technologies. By operating directly in-market, Myriad brings together capital, enterprise relationships, and operator insight in a way built for adoption — not just discovery.

In practice, the year validated Myriad’s core thesis: venture provides a powerful source of real-time business intelligence, while enterprises continue to grapple with Innovator’s Dilemma.

Over the course of the year:

• Founders increasingly engaged Myriad not just for capital, but for access, feedback, and enterprise pathways.
• Enterprise partners moved from one-off evaluations to sustained, multi-meeting collaboration and multi-year commercial engagements.
• Founder and enterprise engagement reinforced one another, strengthening the flywheel across the Myriad ecosystem.
• We also welcomed Sarah Adams as Partner and Head of Platform, further strengthening our support for founders as they scale and corporate partners as they internalize new AI technologies.

Myriad By the Numbers

Since its inception, Myriad Venture Partners has:

• 900+ commercial introductions between startups and enterprises
• 70 proof-of-concept (POC) engagements, resulting in 24 commercial contracts
• 26 new portfolio companies added
• 119 Fortune 500 companies are now using technology developed by our portfolio companies
• Myriad portfolio companies have raised over $932M in capital since inception, with $223M raised in 2025
• Myriad and portfolio company announcements have been key drivers in the VC, AI, B2B, and deep tech media landscapes, resulting in 374 unique articles with a combined reach of over 431.9 million readers since our launch

These indicators collectively reflect a platform that compounds over time. As many early-stage companies struggled to convert interest into real-world use, Myriad-backed teams demonstrated what it takes to move from early interest to scaling enterprise adoption.

What Success Looked Like in Practice

Across the portfolio, late-2025 milestones reinforced a consistent pattern: companies built for enterprise realities outperform.

Portfolio highlights

• Wexler.ai expanded adoption among top-tier law firms following the launch of its redesigned fact intelligence platform.
• Patlytics deepened its role as an end-to-end intelligence layer for IP workflows through new Fortune 500 partnerships, AM100 law firm engagement, and expanded legal leadership.‍
• Not Diamond launched SOTA algorithms to automatically optimize and adapt prompts and agents across models, significantly enhancing accuracy and outperforming weeks of manual prompt engineering in minutes.‍
• OpenHands continued to scale its enterprise-secure agent platform, enabling governed deployment of autonomous agents in cloud environments.‍
• Quadric hit a revenue inflection with product revenues more than tripling as the company accelerates design-win momentum, driven by growing adoption of its processor IP across edge LLM, automotive, and enterprise vision applications.‍
• Mojave ramped up production of their advanced commercial HVAC systems to meet sales demand from several large enterprises and regional sales to C&I customers.

To learn more about other exciting developments from our portfolio, check out our latest blog posts.

Network Advantage: The System Behind Repeatable Adoption

The defining feature of the Myriad Model is its network. The Myriad team’s deep operational and market experience, combined with an impressive network of founders, operators, and enterprise partners, creates early insights, practical context and helps turn early conversations into sustained collaboration and value creation.

A critical aspect of our network and momentum is engagement with Myriad’s Executive Advisory Board (EAB) and long-standing corporate partners. The EAB evolved from a foundational concept into a force multiplier in 2025, expanding to nearly 30 C-suite operators across technology, financial services, and professional services. Advisors — including Fortune 100 CIOs, CTOs, Chief AI Officers, and enterprise technology leaders — engaged directly in product feedback, go-to-market strategy, diligence, and early enterprise conversations, giving founders sharper insight into how enterprise buyers evaluate, adopt, and scale new technology.

In parallel, and another key pillar of the Myriad Model, Myriad launched its Strategic Advisory Board (SAB), anchored by four inaugural public company members. The SAB enables focused, high-impact engagement across each enterprise's critical functional areas and top strategic goals, complementing our EAB and broader Fortune 1000 network.

An example of the Myriad Model in action can be seen through the introduction of native gen AI legal solutions into the legal vertical and into the legal function in corporate enterprises, which resulted in recognition for Myriad as one of Law.com’s 8 Most Active Legal Tech Investors in 2025, highlighting the firm’s ability to back teams built to succeed in demanding enterprise environments.

Founders have also become one of Myriad’s strongest amplifiers — driving inbound deal flow, serving as trusted references for enterprise partners exploring engagement, and reinforcing the platform through real proof points.

• Paul Lee, Patlytics Co-founder & CEO: “The introductions facilitated by the Myriad team across their global enterprise network have led to pivotal partnerships and commercial wins, translating directly into tangible value for Patlytics. These connections have opened doors to new markets, accelerated our product development, and boosted our revenue streams.”
• Veerbhan Kheterpal, Quadric Founder & CEO: “The Myriad Model is unlike any investment approach I’ve seen. They understand the unique challenges startups face and provide the network and expertise needed to support our growth. With Myriad, we’re accelerating a foundation for success.”
• Karthik Kannan, Anvilogic Co-founder & CEO: “My experience working with the Myriad team has been great. Not only did they come in with a strong thesis about Anvilogic and the AI-driven cybersecurity space, but they also have since been consistent in providing us opportunities to meet prospective customers within their extensive network, with whom we have had commercial success.”
• Tomás Hernando Koffman, Not Diamond Co-founder & CEO: “Myriad has been unbelievably valuable as a partner. They've consistently opened doors to Fortune 500 executives, which is critical for our enterprise motion. Beyond intros, they rolled up their sleeves on one of our biggest deals of last year — back-channeling with the buyer's C-suite to help us close our company’s first eight-figure contract. Myriad back their conviction with both capital and time, and they don't need validation from other investors to engage deeply with portfolio companies. It's been a dream partnership that's made a real difference in how we've built the business.”
• Philip Farese, Mojave CEO: “Myriad has been an exceptional partner in our mission to change the nature of air conditioning. Their team not only brings thoughtful insights and advice but also actively opens doors to strategic partners and collaborators who can meaningfully advance our commercialization efforts. The support and relationships Myriad provides are directly strengthening Mojave’s trajectory and expanding the impact of our technology.”

Looking Ahead

For founders, 2025 reinforced that Myriad is a long-term partner beyond the initial check. For enterprises, it demonstrated that innovation can be intentional, secure, and scalable. For LPs, it confirmed that the Myriad Model is working — pairing early insight with deep enterprise engagement to drive repeatable outcomes across the platform.

Our strategy remains consistent: identify enterprise-ready companies early, and help them turn demand into durable adoption.